Modulation of ATP-responses at recombinant rP2X4 receptors by extracellular pH and zinc
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چکیده
منابع مشابه
Contribution of extracellular negatively charged residues to ATP action and zinc modulation of rat P2X2 receptors.
Two histidines are known to be essential for zinc potentiation of rat P2X2 receptors, but the chemistry of zinc coordination would suggest that other residues also participate in this zinc-binding site. There is also a second lower affinity zinc-binding site in P2X2 receptors whose constituents are unknown. To assess whether the extracellular acidic residues of the P2X2 receptor contribute to z...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1999
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0702325